PharmCAT โ Before the Report Becomes a Prescribing Decision
Why this matters
PharmCAT infers pharmacogene diplotype/phenotype from genomic input and links CPIC and annotated guideline/label information to generate a report. The results depend on input completeness, genome build, allele-definition database, tool version, and handling of complex loci such as CYP2D6 and HLA. Record the tool along with data/guideline versions, and do not hide no-call or ambiguous calls. The report does not replace clinician judgment that considers concomitant medications, disease state, organ function, and local policy.
Interpretation boundary
This article explains the concept and the limits of the evidence. It does not provide diagnostic, testing, or treatment decisions for an individual patient.