BioPlayground

Virus Growth Curve Simulator

Simulate Eclipse → Maturation → Burst three-phase virus replication curves. Compare one-step and multi-step growth curves.

ONE-STEP GROWTH CURVE — Bacteriophage T4

10⁰10⁰10¹10²10³10⁴01530456075Time (hours)PFU/mL (log)EclipseMaturationRelease

GROWTH CURVE PHASES

  • Eclipse period — Virus uncoats; no infectious particles recoverable from lysed cells.
  • Maturation — New virions assemble intracellularly but are not yet released.
  • Burst / Release — Mature virions released by lysis or budding. Burst size = PFU per cell.
  • One-step: High MOI (≥5), synchronous infection, single cycle. Multi-step: Low MOI (<1), multiple rounds.