Mango Medical
Mango Medical is an AI agent-based medical solution that fully automates orthopedic surgical planning based on patients' computed tomography (CT scan) and X-ray data. Headquartered in Freising, Germany, this innovative healthcare startup was founded by Adrian Kilian and Jorge Padilla Perez and officially launched its solution in the market through the Y Combinator W26 batch in March 2026. The platform ranges from complex medical image analysis to 3D reconstruction and anatomical landmark identification.
Mango Medical is an AI agent-based medical solution that fully automates orthopedic surgical planning based on patients' computed tomography (CT) scans and X-ray data. Headquartered in Freising, Germany, and founded by Adrian Kilian and Jorge Padilla Perez, this innovative healthcare startup officially launched its solution in the market through the Y Combinator W26 batch in March 2026. The platform connects all processes, from complex medical image analysis to 3D reconstruction and automatic detection of anatomical landmarks, culminating in patient-specific surgical simulations, into a single, seamless end-to-end pipeline.
Traditional orthopedic surgical planning has been inefficient, requiring highly skilled teams of clinical engineers to manually analyze patient medical images and design bone models and implant sizes over several days. To revolutionize this high-cost, low-efficiency process, Mango Medical has boldly adopted foundation models and an agentic AI architecture. Just as an experienced navigation agent precisely analyzes complex road conditions and unpredictable routes to provide the optimal driving route in real-time, this system reviews the patient's skeletal data from multiple angles and calculates the optimal 3D insertion angle and stable fixation size for the implant within minutes.
This solution provides significant value, particularly in orthopedic surgical fields requiring high precision, such as total joint replacement. When implant manufacturers or hospitals upload patient DICOM-format medical images via a cloud API, the system automatically reconstructs the target skeleton into a 3D mesh file and identifies reference points. Subsequently, the AI planner agent analyzes the bone's density and angle to suggest suitable implant types and paths, and pre-simulates potential surgical risks. The resulting 3D printing file (STL/3MF) for surgical guidance is directly used to create patient-specific alignment tools that clinicians can use in actual surgery.
💻 System Requirements
8GB+ (RTX 3060 or higher recommended when using a local GPU; a local GPU is not required when using a cloud API)
Approximately 2GB when downloading the model file
⚡ Installation
4-1. Quick Start
# Mango Medical is provided as an enterprise API, allowing you to call it via curl without the need for separate local package installations.
curl -X POST https://api.mangomedical.io/v1/plans \
-H "Authorization: Bearer YOUR_API_KEY" \
-F "ct_scan=@patient_ct.zip"
4-2. Detailed installation
# Setting up the Python client environment for API integration
pip install requests pillow
🧬 Bio Use Cases
Precise Mapping of Shoulder Arthroplasty Implants
Using the Mango Medical API, upload a patient's shoulder joint CT data (DICOM format), and leverage the AI agent's path generation optimization to fine-tune the three-dimensional insertion angle in 0.5-degree increments, determining and mapping the optimal implant size within 2 minutes.
3D Printing of Patient-Specific Surgical Guides
Calculate the femoral alignment axis using an automated landmark detection algorithm, and output the STL file for the surgical guide template in real-time. Combine this with a 3D printing device to provide high-precision resection guides for immediate use in the clinical setting.
Virtual Surgery Risk Simulation and Bone Fracture Prediction
Detect the pressure and stress applied to the bone during implant insertion using a simulation model, and visualize potential bone fracture or fracture risk areas in 3D, minimizing potential risks and complications that may occur during surgery.
FAQ
What is Mango Medical?
Mango Medical is an AI agent-based medical solution that fully automates orthopedic surgical planning based on patients' computed tomography (CT) scans and X-ray data. Headquartered in Freising, Germany, and founded by Adrian Kilian and Jorge Padilla Perez, this innovative healthcare startup officially launched its solution in the market through the Y Combinator W26 batch in March 2026. The platform connects all processes, from complex medical image analysis to 3D reconstruction and automatic detection of anatomical landmarks, culminating in patient-specific surgical simulations, into a single, seamless end-to-end pipeline. Traditional orthopedic surgical planning has been inefficient, requiring highly skilled teams of clinical engineers to manually analyze patient medical images and design bone models and implant sizes over several days. To revolutionize this high-cost, low-efficiency process, Mango Medical has boldly adopted foundation models and an agentic AI architecture. Just as an experienced navigation agent precisely analyzes complex road conditions and unpredictable routes to provide the optimal driving route in real-time, this system reviews the patient's skeletal data from multiple angles and calculates the optimal 3D insertion angle and stable fixation size for the implant within minutes. This solution provides significant value, particularly in orthopedic surgical fields requiring high precision, such as total joint replacement. When implant manufacturers or hospitals upload patient DICOM-format medical images via a cloud API, the system automatically reconstructs the target skeleton into a 3D mesh file and identifies reference points. Subsequently, the AI planner agent analyzes the bone's density and angle to suggest suitable implant types and paths, and pre-simulates potential surgical risks. The resulting 3D printing file (STL/3MF) for surgical guidance is directly used to create patient-specific alignment tools that clinicians can use in actual surgery.
When should I use Mango Medical?
Mango Medical is an AI agent-based medical solution that fully automates orthopedic surgical planning based on patients' computed tomography (CT scan) and X-ray data. Headquartered in Freising, Germany, this innovative healthcare startup was founded by Adrian Kilian and Jorge Padilla Perez and officially launched its solution in the market through the Y Combinator W26 batch in March 2026. The platform ranges from complex medical image analysis to 3D reconstruction and anatomical landmark identification.
What is a biomedical use case for Mango Medical?
Precise Mapping of Shoulder Arthroplasty Implants: Using the Mango Medical API, upload a patient's shoulder joint CT data (DICOM format), and leverage the AI agent's path generation optimization to fine-tune the three-dimensional insertion angle in 0.5-degree increments, determining and mapping the optimal implant size within 2 minutes.
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