- Viral infectious diseases are a category of diseases in which viruses infect human cells and cause illness; they encompass multiple infections rather than referring to a single disease name.
- Viruses can be transmitted through various routes, such as respiratory droplets or particles, contaminated surfaces, transmission during pregnancy, contaminated food or water, infected animals or insects, and sexual contact.
- Viruses enter cells and replicate by utilizing the functions of host cells; during this process, cells may be damaged, altered, or die, and immune responses can cause symptoms.
- Clinical manifestations vary depending on the infecting virus and the affected organs, ranging from mild respiratory symptoms like those of the common cold to severe diseases such as influenza, COVID-19, and HIV.
- Risk and progression can vary not only according to the type of virus and the route of exposure but also according to age, pregnancy status, immune status, underlying conditions, vaccination status, and regional outbreak situations.
- Symptoms range from asymptomatic cases to systemic symptoms and organ dysfunction; some infections resolve acutely, while others may persist or leave complications.
- Diagnosis is made by evaluating symptoms along with exposure history and epidemiological context, and by combining viral antigen, nucleic acid, and antibody tests with assessment of involved organs as necessary.
- Test results must be interpreted considering the timing of the test, specimen quality, prior infection or vaccination, and test performance; a positive or negative result alone cannot definitively determine severity or infectivity.
- Management involves implementing measures to reduce infection spread, assessing symptoms and organ function, providing supportive care such as hydration and rest, and monitoring for complications, tailored to the type and severity of the infection.
- In many viral infections, symptom relief is the focus while the immune system suppresses the infection, and specific antivirals are used only for certain infections. Antibiotics have no effect on viruses themselves.